Radiofrequency Ablation Versus Antiarrhythmic Drug Therapy for Atrial€Fibrillation
نویسندگان
چکیده
Konstantinos C. Siontis, MD, John P.A. Ioannidis, MD, DSC, George D. Katritsis, MB, CHB, BSC, Peter A. Noseworthy, MD, Douglas L. Packer, MD, John D. Hummel, MD, Pierre Jais, MD, PHD, Rungroj Krittayaphong, MD, Llius Mont, MD, PHD, Carlos A. Morillo, MD, Jens Cosedis Nielsen, MD, Hakan Oral, MD, Carlo Pappone, MD, PHD, Vincenzo Santinelli, MD, Rukshen Weerasooriya, MBBS, David J. Wilber, MD, Bernard J. Gersh, MB, CHB, DPHIL, Mark E. Josephson, MD, Demosthenes G. Katritsis, MD, PHD
منابع مشابه
Silent cerebral embolism during catheter ablation of atrial fibrillation: how concerned should we be?
Radiofrequency catheter ablation is recommended with increasing frequency as part of a treatment regimen for both paroxysmal and persistent forms of symptomatic atrial fibrillation (AF), largely because of the relatively poor efficacy of antiarrhythmic medications1 and trials showing improvement in quality of life and reduction in AF in selected patients.2 The ongoing Catheter Ablation Versus A...
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BACKGROUND Although radiofrequency catheter ablation (RFA) has evolved from an experimental procedure to an important treatment option for atrial fibrillation, the relative safety and efficacy of catheter ablation relative to that of antiarrhythmic drug (AAD) therapy has not been established. METHODS AND RESULTS Two separate systematic reviews were conducted: one on RFA and the other on AAD t...
متن کاملCost-effectiveness of radiofrequency catheter ablation compared with antiarrhythmic drug therapy for paroxysmal atrial fibrillation.
BACKGROUND Radiofrequency catheter ablation (RFA) has emerged as an important treatment strategy for atrial fibrillation (AF). The potential cost-effectiveness of RFA for AF, relative to antiarrhythmic drug (AAD) therapy, has not been fully explored from a US perspective. METHODS AND RESULTS We constructed a Markov disease simulation model for a hypothetical cohort of patients with drug-refra...
متن کاملRadiofrequency ablation vs antiarrhythmic drugs as first-line treatment of paroxysmal atrial fibrillation (RAAFT-2): a randomized trial.
IMPORTANCE Atrial fibrillation (AF) is the most common rhythm disorder seen in clinical practice. Antiarrhythmic drugs are effective for reduction of recurrence in patients with symptomatic paroxysmal AF. Radiofrequency ablation is an accepted therapy in patients for whom antiarrhythmic drugs have failed; however, its role as a first-line therapy needs further investigation. OBJECTIVE To comp...
متن کاملHybrid Therapy in the Management of Atrial Fibrillation
Atrial fibrillation is the most common sustained arrhythmia. Because of the sub-optimal outcomes and associated risks of medical therapy as well as the recent advances in non-pharmacologic strategies, a multitude of combined (hybrid) algorithms have been introduced that improve efficacy of standalone therapies while maintaining a high safety profile. Antiarrhythmic administration enhances succe...
متن کاملAntiarrhythmics After Ablation of Atrial Fibrillation (5A Study).
BACKGROUND Atrial arrhythmias are common early after atrial fibrillation (AF) ablation. We hypothesized that empirical antiarrhythmic drug (AAD) therapy for 6 weeks after AF ablation would reduce the occurrence of atrial arrhythmias. METHODS AND RESULTS We randomized consecutive patients with paroxysmal AF undergoing ablation to empirical antiarrhythmic therapy (AAD group) or no antiarrhythmi...
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تاریخ انتشار 2017